Interrupting prolonged sitting improves insulin sensitivity in adults with type 1 diabetes

Regularly interrupting prolonged sitting with brief bouts of simple resistance exercises can improve insulin sensitivity in adults with Type 1 diabetes, even when insulin dosage is standardized, according to a study.

The study included 8 adults on continuous subcutaneous insulin infusion (CSII) therapy, who participated in two 6-hour sessions: one with uninterrupted sitting and another with sitting interrupted every 30 minutes by 3-minute resistance activities.

Results showed no significant difference in glucose response between the conditions. However, insulin levels were notably higher when sitting was interrupted with physical activity, suggesting an enhanced insulin response.

The authors suggested that future research is needed to explore the underlying mechanisms and to assess if similar benefits apply to patients on multiple daily injections.

Reference
Larsen R, Taylor F, Dempsey PC, et al. Effect of Interrupting Prolonged Sitting with Frequent Activity Breaks on Postprandial Glycemia and Insulin Sensitivity in Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy: A Randomized Crossover Pilot Trial. Diabetes Technol Ther. 2024;doi: 10.1089/dia.2024.0146. Epub ahead of print. PMID: 39506625.